By embracing change and showing dedicated effort, HLB Therapeutics is taking a leap forward as a progressive and dynamic global pharmaceutical company.

Take-off Stage
November
2021
  • Changed company name to HLB Therapeutics Co., Ltd.
September
2018
  • Completed merger with YS Pharm Co., Ltd.
April
2018
  • Phase 3 clinical study protocol (ARISE-3) protocol for the treatment of dry eye syndrome (RGN-259) accepted by the US
  • Acquired an additional stake in ReGenTree, LLC (61.5%)
  • Phase 1 clinical study protocol for combination therapy with OKN-007 and temozolomide in patients with newly diagnosed glioblastoma accepted by the US FDA as an investigator initiated trial agreed by the US FDA
August
2016
  • Phase 3 clinical study (ARISE-2) protocol for Dry Eye Syndrome (RGN-259) accepted  by the US FDA
  • Obtained designation of OKN-007 as orphan drug by the US FDA for a treatment of glioblastoma multiforme
February
2016
  • Acquired the development pipeline, OKN-007, for the treatment of Glioblastoma from OMRF
Conversion Stage
December
2015
  • Established Oblato, Inc., a wholly owned subsidiary in the United States
August
2015
  •  Phase 2b/3 clinical study (ARISE-1) protocol for Dry Eye Syndrome (RGN-259) accepted by the US FDA
  • Phase 3 clinical study (SEER-1) protocol for neurotrophic keratitis (RGN-259) accepted by the US FDA
July
2015
  • Obtained IND approval by Korea Food and Drug Administration for Phase 2b/3 clinical study protocol of Dry Eye Syndrome (GBT-201)
January
2015
  • Established ReGenTree, LLC, a US joint venture
April
2014
  • Changed company name to GtreeBNT Co., Ltd.
March
2014
  • Executed license agreements of new drug development pipelines, RGN-259 and RGN-137, with RegeneRx Biopharmaceuticals, Inc., a US Biotech company
December
2013
  • RGN-259 designated as orphan drug by the US FDA for a treatment of neurotrophic keratitis
Growing Stage
July
2013
  • Merged with Coreindus Co., Ltd.
December
2011
  • Merged with The Change Co., Ltd.
March
2010
  •  Listed on the KOSDAQ
January
2009
  • Awarded the Prime Minister Award as the ‘2008 Venture Business
  • Moved headquarters to new location
November
2007
  • Awarded the ‘2007 Seongnam Small and Medium Venture Business Award’
June
2000
  • Established Digital Aria Co., Ltd. as a company